报告题目：Rapid method to locate double bonds in unusual fatty acids in foods

报告时间：2018年12月6号 下午1:30

报告地点：国工B楼B2203学术报告厅

主讲嘉宾简介： J. Thomas Brenna，professor in Cornell/ University of Texas at Austin. His research couples Nutrition and Chemistry in a broadly interdisciplinary program.  His research group has been funded by institutes/centers at the NIH (NIGMS, NEI, NICHD, NCCIH) and has included at least one active R01 continuously since 1992. These grants have supported fundamental work in the nutrition of polyunsaturated fatty acids, and development of advanced mass spectrometry instrumentation and techniques.

Most of the work of the Brenna Lab is translational, tying basic research to biomedicine and human nutrition.  Some studies are designed with particular, topical human health questions in mind, and these studies have occasionally had immediate implications. The most prominent examples of this work are animal studies to evaluate the efficacy, safety, and metabolism of food sources of polyunsaturated fatty acids. This work often employs stable isotope tracer techniques and molecular or isotope ratio mass spectrometry to probe metabolism. Other projects, particularly those that develop instrumentation and methods for mass spectrometry techniques, have a longer term payoff. They are sometimes undertaken for the challenge of making measurements that have never been possible previously, with an eye toward eventual applications. An example of this area is the development of a novel gas phase reaction for derivatization of polyunsaturated fatty acids for facile determination of double bond structure, which has found applications associated with safety of edible oils, including detection of trans fatty acids.  More recent research is on nutrition of saturated branched chain fatty acids, a neglected class of dietary fatty acids.  Recent work involves development of methods.